Description

4-Carboxyethynyl-Benzoic Acid is a high-purity, functionalized benzoic acid derivative featuring both a carboxylic acid and an ethynyl (acetylene) group, making it a versatile bifunctional building block. This compound is valued for its role in advanced organic synthesis, particularly in click chemistry and the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages for bioconjugation and polymer functionalization.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Incorporated into polymer backbones or side chains to introduce carboxylic acid functionality for enhanced solubility or reactivity.
• Agrochemical Research: Used in the development of novel herbicides and plant growth regulators.
• Diagnostic Reagents: Employed in the fabrication of probes and sensors due to its bifunctional linker capabilities.

Basic Information

Product Name	4-Carboxyethynyl-Benzoic Acid
CAS No.	10602-02-5
Molecular Formula	C10H6O4
Molecular Weight	190.15 g/mol
Synonyms	4-Ethynylphthalic Acid; 4-(Carboxyethynyl)benzoic Acid; 4-(2-Carboxyethynyl)benzoic Acid; Benzoic acid, 4-(carboxyethynyl)-; 4-Acetylene-1,2-benzenedicarboxylic Acid (non-IUPAC); 4-(1-Carboxyvinyl)benzoic Acid (tautomeric form); Terephthalic acid, 4-ethynyl- (related); 10602-02-5
EINECS	Contact for details

Quality Control

Our 4-Carboxyethynyl-Benzoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.