Description

(3-Methylenecyclobutyl)Methanol is a versatile organic building block featuring a reactive methylene group and a primary alcohol functionality on a strained cyclobutane ring. This unique structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and advanced material research. It is particularly sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), specialty polymers, and agrochemicals. The compound, identified by CAS No. 10555-45-0, offers a compact, functionalized scaffold for introducing cyclobutyl motifs into target structures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the construction of cyclobutane-containing drug candidates, potentially for antiviral, anti-inflammatory, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, or insecticides where the cyclobutyl group can influence biological activity and environmental fate.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored thermal, mechanical, or optical properties.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands or organometallic catalysts for asymmetric synthesis.
• Fragrance & Flavor Chemistry: Potential intermediate for creating unique scent or flavor molecules with novel structural backbones.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening, functionalization, and cycloaddition reactions.

Basic Information

Product Name	(3-Methylenecyclobutyl)Methanol
CAS No.	10555-45-0
Molecular Formula	C6H10O
Molecular Weight	98.14 g/mol
Synonyms	3-Methylenecyclobutanemethanol; (3-Methylenecyclobutyl)carbinol; Cyclobutylidenemethanol; Hydroxymethylmethylenecyclobutane; 3-Methylencyclobutylmethanol; 10555-45-0; (3-Methylen-cyclobutyl)-methanol
EINECS	Contact for details

Quality Control

Our (3-Methylenecyclobutyl)Methanol is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We support custom synthesis and can tailor specifications to meet the stringent requirements of cGMP, ICH guidelines, or other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to minimize potential oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.