Description

2-Adamantanamine Hydrochloride is a high-purity, pharmaceutically relevant organic salt derived from the rigid adamantane cage structure. This compound serves as a critical building block and intermediate in the synthesis of advanced therapeutic agents, particularly in antiviral and neurological drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers developing next-generation treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral drugs, including adamantane-based agents like amantadine and rimantadine derivatives.
• Neurological Research: Used in the development of novel NMDA receptor antagonists and other central nervous system (CNS) active compounds.
• Organic Synthesis Building Block: Utilized to introduce the rigid, lipophilic adamantyl group into complex molecules to modify their physical and biological properties.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic frameworks.
• Chemical Biology & Proteomics: Employed as a scaffold or tag in the design of chemical probes and enzyme inhibitors.
• Catalysis Research: Serves as a ligand precursor for the development of novel metal-organic catalysts.

Basic Information

Product Name	2-Adamantanamine Hydrochloride
CAS No.	10523-68-9
Molecular Formula	C10H17N·HCl
Molecular Weight	187.71 g/mol
Synonyms	2-Adamantylamine Hydrochloride; 2-Aminoadamantane Hydrochloride; 1-Aminotricyclo[3.3.1.13,7]decane Hydrochloride; Adamantan-2-amine Hydrochloride; 2-Adamantanamine HCl; NSC 113926; 2-ADAMANTANAMINE HYDROCHLORIDE; 2-ADAMANTYLAMINE HYDROCHLORIDE
EINECS	234-073-5

Quality Control

Our 2-Adamantanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.