Description

4-Chlorosulfonyl-Benzoic Acid Ethyl Ester is a versatile and reactive organic intermediate, primarily valued for its dual functional groups which enable its use in sophisticated multi-step synthesis. This compound is essential for the production of high-value fine chemicals and active pharmaceutical ingredients (APIs), where precise molecular construction is critical. It is a key building block for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and anti-glaucoma agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that require a sulfonyl chloride moiety for activity.
• Dye and Pigment Manufacturing: Serves as a key intermediate for creating sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, altering properties like hydrophilicity, ion-exchange capacity, or adhesion.
• Ligand and Catalyst Development: Useful in organic and organometallic chemistry for constructing complex ligands used in catalysis and material science.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Chlorosulfonyl-Benzoic Acid Ethyl Ester
CAS No.	10486-51-8
Molecular Formula	C9H9ClO4S
Molecular Weight	248.68 g/mol
Synonyms	Ethyl 4-(Chlorosulfonyl)benzoate; Benzoic acid, 4-(chlorosulfonyl)-, ethyl ester; 4-(Chlorosulfonyl)benzoic Acid Ethyl Ester; Ethyl p-Chlorosulfonylbenzoate; p-Carbethoxyphenylsulfonyl Chloride; 4-Carbethoxybenzenesulfonyl Chloride; NSC 403107
EINECS	234-001-6

Quality Control

Every batch of 4-Chlorosulfonyl-Benzoic Acid Ethyl Ester is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.