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Boc-11-Aminoundecanoic Acid CAS NO 10436-25-6


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CAS No.:10436-25-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Boc-11-Aminoundecanoic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis and peptide research. This compound serves as a critical building block for the controlled introduction of an 11-carbon spacer arm with a primary amine functionality, enabling precise molecular design. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel therapeutic peptides, bioconjugates, and specialized polymers.

Application

  • Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of long-chain peptide constructs, providing a protected amine for sequential coupling.
  • Linker Chemistry: Used to create spacer arms or linkers in bioconjugation, connecting drugs, dyes, or other molecules to antibodies, proteins, or nanoparticles.
  • Polymer Modification: Serves as a functional monomer or end-group modifier for creating amine-functionalized polymers with specific chain lengths for material science applications.
  • Prodrug Development: Employed in the design of prodrugs where a peptide-based cleavable linker is required for targeted drug release.
  • Surface Functionalization: Used to coat surfaces with amine groups for subsequent immobilization of biomolecules in biosensor and diagnostic device manufacturing.
  • Chemical Biology Probes: Integral to synthesizing probes and tools for studying biological processes, leveraging its stable tert-butoxycarbonyl (Boc) protecting group.

Basic Information

Product Name Boc-11-Aminoundecanoic Acid
CAS No. 10436-25-6
Molecular Formula C₁₆H₃₁NO₄
Molecular Weight 301.42 g/mol
Synonyms 11-[(tert-Butoxycarbonyl)amino]undecanoic acid; N-Boc-11-aminoundecanoic acid; N-(tert-Butoxycarbonyl)-11-aminoundecanoic acid; Boc-NH-(CH2)10-COOH; 11-Aminoundecanoic acid N-Boc derivative; tert-Butyl (11-carboxyundecyl)carbamate; UNII-6Q5U8T85F4
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Quality Control

Our Boc-11-Aminoundecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 85 - 90 °C
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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