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Boc-11-Aminoundecanoic Acid CAS NO 10436-25-6
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CAS No.:10436-25-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Boc-11-Aminoundecanoic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis and peptide research. This compound serves as a critical building block for the controlled introduction of an 11-carbon spacer arm with a primary amine functionality, enabling precise molecular design. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel therapeutic peptides, bioconjugates, and specialized polymers.
Application
- Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of long-chain peptide constructs, providing a protected amine for sequential coupling.
- Linker Chemistry: Used to create spacer arms or linkers in bioconjugation, connecting drugs, dyes, or other molecules to antibodies, proteins, or nanoparticles.
- Polymer Modification: Serves as a functional monomer or end-group modifier for creating amine-functionalized polymers with specific chain lengths for material science applications.
- Prodrug Development: Employed in the design of prodrugs where a peptide-based cleavable linker is required for targeted drug release.
- Surface Functionalization: Used to coat surfaces with amine groups for subsequent immobilization of biomolecules in biosensor and diagnostic device manufacturing.
- Chemical Biology Probes: Integral to synthesizing probes and tools for studying biological processes, leveraging its stable tert-butoxycarbonyl (Boc) protecting group.
Basic Information
| Product Name | Boc-11-Aminoundecanoic Acid |
| CAS No. | 10436-25-6 |
| Molecular Formula | C₁₆H₃₁NO₄ |
| Molecular Weight | 301.42 g/mol |
| Synonyms | 11-[(tert-Butoxycarbonyl)amino]undecanoic acid; N-Boc-11-aminoundecanoic acid; N-(tert-Butoxycarbonyl)-11-aminoundecanoic acid; Boc-NH-(CH2)10-COOH; 11-Aminoundecanoic acid N-Boc derivative; tert-Butyl (11-carboxyundecyl)carbamate; UNII-6Q5U8T85F4 |
| EINECS | Contact for details |
Quality Control
Our Boc-11-Aminoundecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | 85 - 90 °C |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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