Description

[(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxohexyl] Hydrogen Sulfate is a high-purity, chemically defined derivative of N-acetylneuraminic acid, a critical sialic acid. This compound serves as a valuable biochemical building block and reference standard for advanced research and development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly those working on carbohydrate-based therapeutics, enzyme substrates, and glycobiology studies.

Application

• Biochemical Research: As a key intermediate or reference standard in glycobiology and sialic acid metabolism studies.
• Pharmaceutical Development: Potential use as a precursor or building block in the synthesis of novel carbohydrate-based drugs and vaccines.
• Enzymology: Serving as a specific substrate for studying sialidases (neuraminidases) and other glycosyl hydrolases.
• Diagnostic Reagent Manufacturing: Used in the development of high-sensitivity diagnostic assays and kits targeting sialylated biomarkers.
• Academic Research: A critical tool for investigating cell surface recognition, signaling pathways, and microbial pathogenesis involving sialic acids.

Basic Information

Product Name	[(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxohexyl] Hydrogen Sulfate
CAS No.	10356-99-7
Molecular Formula	C8H15NO10S
Molecular Weight	317.27 g/mol
Synonyms	5-Acetamido-2,3,4-trihydroxy-6-oxohexyl hydrogen sulfate; N-Acetylneuraminic acid 9-sulfate; Neu5Ac9S; Sialic acid 9-sulfate; 9-O-Sulfo-N-acetylneuraminic acid; (2R,3S,4R,5R)-5-Acetamido-2,3,4-trihydroxy-6-oxohexyl hydrogen sulphate; 9-Sulfo-5-N-acetylneuraminic acid
EINECS	Contact for details

Quality Control

Our [(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxohexyl] Hydrogen Sulfate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.