Description

n-[tert-Butoxycarbonyl]-L-Serine, Compound With Dicyclohexylamine (1:1) is a high-purity, protected amino acid derivative, specifically a Boc-L-serine dicyclohexylamine salt. This compound is a critical building block in solid-phase peptide synthesis (SPPS), offering enhanced stability and solubility for the controlled introduction of L-serine residues. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing therapeutic peptides, peptidomimetics, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected serine derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediate: In the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Labeling: For introducing serine moieties into biomolecules for diagnostic or targeting purposes.
• Fine Chemical Synthesis: As a chiral synthon in the asymmetric synthesis of complex natural products and specialty chemicals.
• Biochemical Research: Used in enzymatic studies, substrate preparation, and as a standard in analytical method development.

Basic Information

Product Name	n-[tert-Butoxycarbonyl]-L-Serine, Compound With Dicyclohexylamine (1:1)
CAS No.	10342-06-0
Molecular Formula	C20H38N2O5
Molecular Weight	386.53 g/mol
Synonyms	Boc-L-Serine Dicyclohexylamine Salt; Boc-Ser-OH·DCHA; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid compound with dicyclohexylamine (1:1); N-Boc-L-serine dicyclohexylammonium salt; N-α-Boc-L-serine DCHA salt; tert-Butoxycarbonyl-L-serine dicyclohexylamine salt; Boc-Ser-DCHA; L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, compd. with dicyclohexylamine (1:1)
EINECS	Contact for details

Quality Control

Our n-[tert-Butoxycarbonyl]-L-Serine DCHA salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for peptide synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.