Description

(R)-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is a high-purity chiral amine salt, a key building block in advanced organic synthesis. Its enantiomeric purity makes it a critical intermediate for developing active pharmaceutical ingredients (APIs) and fine chemicals with specific stereochemical requirements. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring the (R)-enantiomer of the 1-aminoindane scaffold.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	10305-73-4
Molecular Formula	C9H12N·HCl
Molecular Weight	169.66 g/mol (Free base: 134.20)
Synonyms	(1R)-2,3-Dihydro-1H-inden-1-amine hydrochloride; (R)-1-Aminoindane hydrochloride; (R)-1-Indanamine hydrochloride; (R)-1-Amino-2,3-dihydro-1H-indene hydrochloride; (R)-1-Aminoindan HCl; (R)-1-Indanylammonium chloride; (R)-1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride (related); (R)-1-Aminotetralin hydrochloride (related)
EINECS	Contact for details

Quality Control

Our (R)-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is analyzed to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity (Chiral HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.