Description

(R)-(-)-1-Aminoindan is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its rigid indane scaffold and stereogenic center, making it a versatile intermediate for constructing complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the production of advanced chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Used to develop and synthesize novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Material Science Research: Intermediate in the development of chiral polymers and advanced organic materials with specific optical properties.
• Academic & Industrial R&D: Serves as a standard and starting material in methodological development for organic and medicinal chemistry research.

Basic Information

Product Name	(R)-(-)-1-Aminoindan
CAS No.	10277-74-4
Molecular Formula	C9H11N
Molecular Weight	133.19 g/mol
Synonyms	(1R)-2,3-Dihydro-1H-inden-1-amine; (R)-1-Aminoindane; (R)-1-Indanamine; (-)-(R)-1-Aminoindan; (R)-(-)-1-Aminoindane; (R)-1-Amino-2,3-dihydro-1H-indene; (R)-α-Aminoindane
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Aminoindan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.