Description

Dimethyl 1,1-Cyclobutanedicarboxylate is a high-purity diester building block valued for its unique strained four-membered ring structure. This compound serves as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing cyclobutane-containing drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclobutane ring imparts specific biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, ring-opening polymerizations, and other transformations to introduce the cyclobutane scaffold.
• Material Science Research: Investigated for use in liquid crystals, organic semiconductors, and other advanced functional materials.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex macrocyclic musks and other aroma chemicals.

Basic Information

Product Name	Dimethyl 1,1-Cyclobutanedicarboxylate
CAS No.	10224-72-3
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	1,1-Cyclobutanedicarboxylic Acid Dimethyl Ester; Dimethyl Cyclobutane-1,1-dicarboxylate; Cyclobutane-1,1-dicarboxylic Acid Dimethyl Ester; Methyl 1-Cyclobutanecarboxylate-1-carboxylate; DM-CBD; NSC 66484
EINECS	233-552-3

Quality Control

Our Dimethyl 1,1-Cyclobutanedicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Gravity (20°C)	1.120 - 1.140
Refractive Index (20°C)	1.440 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.