Description

1,2-Diethoxypropane CAS NO 10221-57-5 is a versatile acetal compound primarily used as a protecting group reagent and solvent in advanced organic synthesis. Its value lies in its ability to act as a moisture scavenger and a precursor for generating ketene acetals, making it crucial for reactions sensitive to water. This chemical is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• As a protecting group for carbonyls (diols) in multi-step organic synthesis, particularly for sensitive pharmaceutical intermediates.
• As a dehydrating agent and moisture scavenger in reaction systems requiring anhydrous conditions.
• As a precursor for ketene acetal generation, used in Claisen rearrangements and other carbon-carbon bond forming reactions.
• As a specialty solvent and reaction medium in organometallic chemistry and Grignard reactions.
• In the synthesis of flavor and fragrance compounds where specific acetal functionalities are required.
• In polymer chemistry as a cross-linking agent or modifier for resins and coatings.

Basic Information

Product Name	1,2-Diethoxypropane
CAS No.	10221-57-5
Molecular Formula	C7H16O2
Molecular Weight	132.20 g/mol
Synonyms	1,2-Diethoxypropane; Propane, 1,2-diethoxy-; Acetaldehyde ethyl propyl acetal; 2-Ethoxy-1-ethoxypropane; Ethyl propyl acetal of acetaldehyde; 1,2-Diethoxy-propane; 10221-57-5
EINECS	233-549-7

Quality Control

Our 1,2-Diethoxypropane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC analysis for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, water content, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizers. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to minimize moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.395 - 1.399
Density (20°C)	0.825 - 0.835 g/mL
Boiling Point	Approx. 132 - 136 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.