Description

(1R,4S)-n-[[(1S,4R)-Bicyclo[2.2.1]Heptan-2α-Yl]Methyl]Bicyclo[2.2.1]Heptane-2β-Methanamine is a high-purity, chiral bicyclic amine building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Used to develop proprietary ligands for transition metal catalysis, enabling highly enantioselective synthetic transformations.
• Agrochemical Research: Employed as a building block for creating new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in organic methodology and stereochemistry.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, stereochemically-defined odorants and flavor compounds.

Basic Information

Product Name	(1R,4S)-n-[[(1S,4R)-Bicyclo[2.2.1]Heptan-2α-Yl]Methyl]Bicyclo[2.2.1]Heptane-2β-Methanamine
CAS No.	10171-76-3
Molecular Formula	C15H25N
Molecular Weight	219.37 g/mol
Synonyms	2β-[[[(1S,4R)-Bicyclo[2.2.1]hept-2-yl]methyl]amino]methyl]-(1R,4S)-bicyclo[2.2.1]heptane; (1R,4S)-2β-[[[(1S,4R)-2-Norbornyl]methyl]amino]methyl]norbornane; endo,endo-Bis(norbornylmethyl)amine (specific isomer); Chiral norbornane-based diamine; Bicyclo[2.2.1]heptane-2-methanamine, N-[(1S,4R)-bicyclo[2.2.1]hept-2-ylmethyl]-, (1R,4S)-; endo-N-[(endo-2-Norbornyl)methyl]-2-norbornanemethylamine
EINECS	Contact for details

Quality Control

Our (1R,4S)-n-[[(1S,4R)-Bicyclo[2.2.1]Heptan-2α-Yl]Methyl]Bicyclo[2.2.1]Heptane-2β-Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.