Description

3-Deoxy-D-Manno-Oct-2-Ulosonic Acid is a high-purity, advanced biochemical intermediate, also known as KDO. This compound is a critical building block in the synthesis of bacterial lipopolysaccharides (LPS) and other complex glycans. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel antibiotics, vaccines, and diagnostic tools.

Application

• Pharmaceutical Research & Development: A key precursor in the synthesis of bacterial cell wall components for antibiotic discovery and vaccine development.
• Glycobiology Studies: Used as a standard and building block for studying carbohydrate metabolism, enzyme mechanisms, and glycosylation pathways.
• Bioconjugate Chemistry: Serves as a specialized linker or spacer molecule in the creation of glycoconjugates for targeted drug delivery systems.
• Diagnostic Reagent Manufacturing: Employed in the production of high-specificity reagents for detecting bacterial infections and related inflammatory markers.
• Enzymatic Synthesis: Acts as a substrate for enzymes like CMP-KDO synthetase in the enzymatic production of complex oligosaccharides.
• Academic & Industrial Research: Fundamental material for investigating Gram-negative bacterial pathogenesis and host immune responses.

Basic Information

Product Name	3-Deoxy-D-Manno-Oct-2-Ulosonic Acid
CAS No.	10149-14-1
Molecular Formula	C8H14O8
Molecular Weight	238.19 g/mol
Synonyms	KDO; 3-Deoxy-D-manno-oct-2-ulosonic acid; 3-Deoxy-D-manno-octulosonic acid; 2-Keto-3-deoxy-D-manno-octonic acid; 3-Deoxy-D-manno-2-octulosonic acid; D-3-Deoxy-manno-octulosonic acid; 3-Deoxy-D-arabino-heptulosonic acid 7-phosphate (related); (4R,5R,6R)-4,5,6-Trihydroxy-2-oxooctanoic acid
EINECS	233-403-1

Quality Control

Our 3-Deoxy-D-Manno-Oct-2-Ulosonic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research and production. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	-30° to -40° (c=1 in H2O)
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.