Description

(2S,3R)-2-Amino-3-Hydroxy-Pentanoic Acid is a non-proteinogenic amino acid derivative with a defined stereochemistry, making it a valuable chiral building block for advanced synthesis. This compound is essential for researchers and manufacturers requiring high-purity, stereochemically pure intermediates for pharmaceutical and biochemical applications. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and as a precursor for complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly protease inhibitors and other biologically active molecules.
• Peptide Research & Synthesis: Used to incorporate specific stereocenters into custom peptides and peptidomimetics for structure-activity relationship (SAR) studies.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective chemical reactions to create complex molecular architectures.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2S,3R)-2-Amino-3-Hydroxy-Pentanoic Acid
CAS No.	10148-67-1
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxypentanoic acid; (2S,3R)-3-Hydroxy-2-aminopentanoic acid; L-threo-3-Hydroxy-2-aminopentanoic acid; β-Hydroxy-norvaline; (2S,3R)-3-Hydroxynorvaline; (2S,3R)-2-Amino-3-hydroxypentanoate; 2-Amino-3-hydroxypentanoic acid (2S,3R)-isomer
EINECS	Contact for details

Quality Control

Our (2S,3R)-2-Amino-3-Hydroxy-Pentanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2S,3R)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.