Description

4-(Chlorosulfonyl)Benzoic Acid is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its dual functionality enables the efficient construction of complex molecules, making it indispensable for creating high-value intermediates. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, anticonvulsants, and carbonic anhydrase inhibitors.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with sulfonylurea or sulfonamide moieties.
• Dyestuff and Pigment Production: Used in the manufacture of sulfonated azo dyes and high-performance pigments.
• Polymer Modification: Functional monomer for introducing sulfonyl chloride groups into polymers for ion-exchange resins or membranes.
• Chemical Research: Versatile reagent in organic chemistry for peptide coupling (as a carboxylic acid activator) and for introducing the sulfonyl chloride functional group.
• Liquid Crystal & OLED Materials: Intermediate in the production of sulfone-based compounds for electronic and display applications.

Basic Information

Product Name	4-(Chlorosulfonyl)Benzoic Acid
CAS No.	10130-89-9
Molecular Formula	C7H5ClO4S
Molecular Weight	220.63 g/mol
Synonyms	4-Carboxybenzenesulfonyl chloride; p-Carboxybenzenesulfonyl chloride; Benzoic acid, 4-(chlorosulfonyl)-; Terephthalic acid, monosulfonyl chloride; 4-Chlorosulfonylbenzoic acid; p-(Chlorosulfonyl)benzoic acid; NSC 403107
EINECS	233-357-5

Quality Control

Our 4-(Chlorosulfonyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) that include assay, impurity profile, and identification data, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.