Description

7-(Trifluoromethyl)-1H-Benzimidazol-2-Amine is a high-value, nitrogen-containing heterocyclic compound featuring a trifluoromethyl substituent. This structure is critical for its role as a versatile and potent building block in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs). It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the unique properties of the benzimidazole core and fluorine atoms into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides, herbicides, and pesticides, where the benzimidazole moiety contributes to biological activity.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of enzyme inhibitors, fluorescent probes, and molecular tools for biological study.
• Catalyst Ligand Synthesis: Utilized to create novel nitrogen-donor ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Benzimidazol-2-Amine
CAS No.	10057-45-1
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	2-Amino-7-(trifluoromethyl)-1H-benzimidazole; 2-Amino-7-(trifluoromethyl)benzimidazole; 7-(Trifluoromethyl)-2-benzimidazolamine; 1H-Benzimidazol-2-amine, 7-(trifluoromethyl)-; 10057-45-1; 7-Trifluoromethyl-1H-benzimidazol-2-ylamine; 7-Trifluoromethyl-2-aminobenzimidazole
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1H-Benzimidazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.