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α-Cyclodextrin CAS NO 10016-20-3


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CAS No.:10016-20-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

α-Cyclodextrin is a cyclic oligosaccharide composed of six α-(1,4)-linked D-glucopyranose units, forming a truncated cone structure with a hydrophobic internal cavity. This unique molecular architecture enables it to form inclusion complexes with a wide variety of guest molecules, significantly enhancing their solubility, stability, and bioavailability. As a key excipient and molecular encapsulation agent, it is essential for industries focused on advanced formulation science, including pharmaceuticals, nutraceuticals, and specialty chemicals.

Application

  • Pharmaceutical Formulations: Used as a complexing agent to improve the aqueous solubility, dissolution rate, and chemical stability of poorly soluble active pharmaceutical ingredients (APIs).
  • Food & Flavor Industry: Acts as a stabilizer and delivery system for volatile flavors, fragrances, and sensitive nutrients, protecting them from oxidation, heat, and light degradation.
  • Cosmetics & Personal Care: Employed to solubilize active ingredients, control odor release, and enhance the stability of formulations in creams, lotions, and serums.
  • Analytical Chemistry & Separation Science: Serves as a chiral selector in capillary electrophoresis and HPLC columns for the enantiomeric separation of racemic mixtures.
  • Chemical Synthesis & Catalysis: Functions as a green, water-soluble host in supramolecular chemistry to modify reaction rates, selectivity, and to stabilize reactive intermediates.
  • Agrochemicals: Enhances the stability and controlled release of pesticides and herbicides, improving their efficacy and environmental profile.

Basic Information

Product Name α-Cyclodextrin
CAS No. 10016-20-3
Molecular Formula C36H60O30
Molecular Weight 972.84 g/mol
Synonyms α-Cyclodextrin; α-CD; Cyclohexaamylose; Schardinger's α-dextrin; α-Cycloamylose; Cyclomaltohexaose; α-Cyclodextrin hydrate; 1,4-α-D-Glucopyranosyl cyclic polymer
EINECS 233-007-4

Quality Control

Our α-Cyclodextrin is manufactured under a strict quality management system. We offer grades suitable for various applications, including pharmaceutical (USP/EP), food (FCC), and high-purity research standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and caking.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 11.0 %
Residue on Ignition ≤ 0.1 %
Specific Rotation +147° to +152°
Heavy Metals ≤ 10 ppm
Microbiological Control As per grade requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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