Description

4'-Chloro-2-Fluoro-n-(2-Hydroxyethyl)Acetanilide is a specialized organic intermediate featuring a unique halogenated aniline structure with a hydroxyethyl side chain. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and other fine chemical products where precise molecular modification is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the chloro and fluoro substituents contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating specialized aromatic amines used in electronic display technologies.
• Dye & Pigment Intermediate: Employed in the production of high-performance, halogenated azo dyes and pigments for industrial applications.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this exact molecular framework.

Basic Information

Product Name	4'-Chloro-2-Fluoro-n-(2-Hydroxyethyl)Acetanilide
CAS No.	10016-08-7
Molecular Formula	C10H11ClFNO2
Molecular Weight	231.65 g/mol
Synonyms	N-(2-Hydroxyethyl)-4'-chloro-2-fluoroacetanilide; 2-Chloro-5-[(2-hydroxyethyl)amino]fluorobenzene; 4-Chloro-2-fluoro-N-(2-hydroxyethyl)aniline; Acetamide, N-(2-hydroxyethyl)-2-fluoro-4'-chloro-; 2-Fluoro-4'-chloro-N-(2-hydroxyethyl)acetanilide; N-(2-Hydroxyethyl)-2-fluoro-4-chloroacetanilide; 10016-08-7 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4'-Chloro-2-Fluoro-n-(2-Hydroxyethyl)Acetanilide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.