Description

4-Nitrophenylalanine is a specialized aromatic amino acid derivative where a nitro group is introduced at the para position of the phenyl ring. This functionalization makes it a valuable chiral building block and a key intermediate in organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel bioactive compounds, peptide mimetics, and advanced materials. The compound's unique structure allows for further chemical modifications, enabling the exploration of structure-activity relationships in drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of more complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Research: Used as a non-natural, modified amino acid residue in peptide synthesis to study enzyme inhibition and receptor binding.
• Biochemical Probe Development: Acts as a substrate or inhibitor in enzymatic assays and studies of amino acid metabolism and transport.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, reductions, and other transformations to create diverse chemical libraries.
• Material Science Research: Investigated for potential use in the development of novel polymers and functionalized surfaces.

Basic Information

Product Name	4-Nitrophenylalanine
CAS No.	1991-83-9
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	(S)-2-Amino-3-(4-nitrophenyl)propanoic acid; p-Nitrophenylalanine; 4-Nitro-DL-phenylalanine; 3-(4-Nitrophenyl)alanine; 2-Amino-3-(4-nitrophenyl)propionic acid; H-Phe(4-NO2)-OH; F4N
EINECS	217-889-2

Quality Control

Our 4-Nitrophenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.