Description

n-(2,2-Dimethylpropanoyl)-3-(Trifluoromethyl)Aniline is a high-purity, specialized organic intermediate featuring a trifluoromethyl aniline core protected by a pivaloyl (2,2-dimethylpropanoyl) group. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where the trifluoromethyl group is prized for enhancing biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Pharmaceutical Building Block: Used in the research and synthesis of active pharmaceutical ingredients (APIs), particularly in molecules targeting central nervous system (CNS) disorders and inflammatory diseases.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific fluorinated properties.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	n-(2,2-Dimethylpropanoyl)-3-(Trifluoromethyl)Aniline
CAS No.	1939-19-1
Molecular Formula	C13H16F3NO
Molecular Weight	259.27 g/mol
Synonyms	3-(Trifluoromethyl)-N-pivaloylaniline; N-Pivaloyl-3-(trifluoromethyl)aniline; 3'-Trifluoromethylpivalanilide; Pivalic acid 3-trifluoromethylanilide; 2,2-Dimethyl-N-[3-(trifluoromethyl)phenyl]propanamide; α,α-Dimethyl-3'-(trifluoromethyl)propionanilide; N-(3-Trifluoromethylphenyl)pivalamide; 1939-19-1
EINECS	217-729-4

Quality Control

Our n-(2,2-Dimethylpropanoyl)-3-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.