Description

Tetrahydro-2-(tert-Butyloxy)-2H-Pyran is a versatile, highly volatile chemical intermediate featuring a protected hydroxyl group. This compound is valued for its role as a key building block in sophisticated organic synthesis, particularly in the pharmaceutical and fine chemical industries. It is primarily sought after by R&D chemists and process development scientists for constructing complex molecular architectures where selective deprotection is required.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring hydroxyl group protection and subsequent controlled deprotection.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structural motif contributes to specific biological activity.
• Polymer Chemistry: Serves as a monomer or modifying agent in the development of specialty polymers with tailored properties.
• Fine Chemical Production: Employed in the manufacture of complex fragrances, flavors, and dyes where high-purity intermediates are essential.
• Academic & Industrial Research: A valuable reagent in methodological development and exploratory chemistry within R&D laboratories.
• Material Science: Used in surface modification and the creation of novel organic-inorganic hybrid materials.

Basic Information

Product Name	Tetrahydro-2-(tert-Butyloxy)-2H-Pyran
CAS No.	1927-69-1
Molecular Formula	C9H18O2
Molecular Weight	158.24 g/mol
Synonyms	2-(tert-Butoxy)tetrahydro-2H-pyran; 2-tert-Butoxytetrahydropyran; Tetrahydropyran-2-yl tert-butyl ether; 2-tert-Butyloxy-tetrahydropyran; THP-O-t-Bu; TBTHP; 2-(tert-Butoxy)oxane; 2-tert-Butoxyoxane
EINECS	217-683-5

Quality Control

Our Tetrahydro-2-(tert-Butyloxy)-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.428 - 1.432
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.