Description

Ethanone, 2-Chloro-1-Cyclohexyl- is a chlorinated cyclohexyl ketone compound valued for its electrophilic reactivity and structural motif in synthetic organic chemistry. It serves as a versatile intermediate in the preparation of pharmaceuticals, agrochemicals, and specialty functional materials requiring regioselective C–C bond formation or halogen-directed transformations. This compound is primarily utilized by R&D laboratories and fine chemical manufacturers engaged in custom synthesis, process development, and active pharmaceutical ingredient (API) route optimization.

Application

• Key synthetic intermediate in the manufacture of cyclohexyl-substituted pyrazoles and triazoles for crop protection agents
• Building block for novel GABAA receptor modulators and CNS-active pharmaceutical candidates
• Reagent in Friedel–Crafts acylation variants for sterically hindered aromatic systems
• Substrate in nucleophilic substitution reactions to generate chiral β-chloro ketones for asymmetric catalysis
• Starting material for photoacid generators (PAGs) in advanced lithographic resists
• Intermediate in the synthesis of cyclohexyl-containing liquid crystals for display technologies

Basic Information

Product Name	Ethanone, 2-Chloro-1-Cyclohexyl-
CAS No.	1892-09-7
Molecular Formula	C8H13ClO
Molecular Weight	144.64 g/mol
Synonyms	2-Chloro-1-cyclohexylethanone; 2-Chloro-1-cyclohexyl ethanone; 1-(2-Chloroacetyl)cyclohexane; Cyclohexyl chloroacetone; 2-Chloro-1-cyclohexylacetone; α-Chlorocyclohexylacetone; NSC 25504; 2-Chloro-1-cyclohexylethanone hydrochloride (note: free base form is standard)
EINECS	217-572-5

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Testing includes identity confirmation (IR, HPLC retention time matching), assay quantification (HPLC assay ≥98.5%), and impurity profiling per ICH Q3 guidelines. All batches conform to ISO 9001-certified manufacturing protocols and support REACH registration and FDA-compliant documentation packages.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15–25°C) in a dry, well-ventilated area. Avoid exposure to moisture, strong alkalis, and oxidizing agents. Due to its light-sensitive nature, minimize handling under direct illumination and use amber glass or opaque containers for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Odor	Characteristic pungent ketonic odor
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.5%
Residue on Ignition	≤0.1%
Chloride (as Cl⁻)	≤0.05%
Water (KF)	≤0.2%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.