Description

(4-Trifluoromethyl-Phenyl)-Phosphonic Acid is a high-value organophosphorus compound featuring a trifluoromethylphenyl group, which imparts unique electronic and steric properties. This compound is a critical building block in advanced material science and pharmaceutical chemistry, valued for its ability to act as a versatile ligand, catalyst modifier, and functional monomer. It is primarily sought after by researchers and manufacturers in the agrochemical, pharmaceutical, and specialty polymer industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the phosphonic acid moiety.
• Metal-Organic Framework (MOF) & Catalyst Ligand: Acts as an organic linker or ligand in constructing MOFs and homogeneous catalysts, where the phosphonic acid group facilitates strong metal coordination.
• Surface Modification Agent: Employed to functionalize metal oxides (e.g., titanium dioxide, alumina) and other surfaces to alter wettability, corrosion resistance, or adhesion properties.
• Flame Retardant Additive: Incorporated into polymer formulations as a phosphorus-based flame retardant, contributing to char formation and reduced flammability.
• Electrolyte Additive for Batteries: Investigated for use in lithium-ion battery electrolytes to improve stability at high voltages and enhance cycle life.

Basic Information

Product Name	(4-Trifluoromethyl-Phenyl)-Phosphonic Acid
CAS No.	1869-27-8
Molecular Formula	C7H6F3O3P
Molecular Weight	226.09 g/mol
Synonyms	p-(Trifluoromethyl)phenylphosphonic Acid; (4-Trifluoromethyl)benzenephosphonic Acid; [4-(Trifluoromethyl)phenyl]phosphonic Acid; 4-(Trifluoromethyl)phenylphosphonic Acid; Phosphonic acid, P-[4-(trifluoromethyl)phenyl]-; α,α,α-Trifluoro-p-tolylphosphonic Acid; 4-Trifluoromethylbenzenephosphonic Acid
EINECS	217-476-5

Quality Control

Our (4-Trifluoromethyl-Phenyl)-Phosphonic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-intermediate synthesis and other regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.