Description

8-Methyl-2-Trifluoromethylquinoline is a high-purity, fluorinated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of the quinoline scaffold and the trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialized ligands for catalysis and functional organic materials, including liquid crystals and OLED components.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.

Basic Information

Product Name	8-Methyl-2-Trifluoromethylquinoline
CAS No.	1860-46-4
Molecular Formula	C11H8F3N
Molecular Weight	211.18 g/mol
Synonyms	2-(Trifluoromethyl)-8-methylquinoline; 8-Methyl-2-(trifluoromethyl)quinoline; Quinoline, 8-methyl-2-(trifluoromethyl)-; 2-Trifluoromethyl-8-methylquinoline; 1860-46-4; 8-Methyl-2-trifluoromethyl-quinoline; 8-Methyl-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.