Description

Spiro[1,3-Dioxolane-2,3'-[5α]Cholestane] is a high-purity, steroidal spiro compound of significant interest in advanced organic synthesis and pharmaceutical research. This specialized chemical serves as a crucial chiral building block and protective group intermediate, enabling the synthesis of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Acts as a key chiral synthon in the research and development of novel steroid-based therapeutics and other bioactive molecules.
• Organic Synthesis Building Block: Used as a versatile intermediate for constructing complex molecular architectures, particularly where the spiro[1,3-dioxolane] moiety is required as a protective group or structural element.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and plant growth regulators that leverage steroidal frameworks.
• Material Science Research: Investigated for potential applications in the development of advanced organic materials, such as liquid crystals or chiral dopants.
• Academic & Industrial R&D: Serves as a reference standard and starting material in methodological studies and process chemistry development within university and corporate laboratories.

Basic Information

Product Name	Spiro[1,3-Dioxolane-2,3'-[5α]Cholestane]
CAS No.	1858-14-6
Molecular Formula	C₃₀H₅₀O₂
Molecular Weight	442.72 g/mol
Synonyms	5α-Cholestane-3β-ol, cyclic 2,3-(ethylene ketal); 3β-Hydroxy-5α-cholestane 2,3-ethylene ketal; 5α-Cholestane-3β-ol, cyclic ethylene ketal; Spiro[1,3-dioxolane-2,3'-5α-cholestane]; (3β)-5α-Cholestane-3-ol cyclic 2,3-ethylene ketal; Cholestane-3β-ol ethylene ketal; 3β-(1,3-Dioxolan-2-yl)-5α-cholestane
EINECS	Contact for details

Quality Control

Our Spiro[1,3-Dioxolane-2,3'-[5α]Cholestane] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support custom synthesis and can tailor purity grades to meet specific research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.