Description

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone is a high-purity brominated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters as a versatile electrophilic reagent, enabling the introduction of the 2-bromoacetyl moiety into complex molecular architectures under controlled conditions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of various drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its reactive halogen for heterocycle formation.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in asymmetric catalysis and material science.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Fine Chemical Manufacturing: Utilized in multi-step custom synthesis for producing high-value, complex organic molecules for various industrial applications.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes.

Basic Information

Product Name	2-Bromo-1-(3,4-Dimethoxyphenyl)Ethanone
CAS No.	1835-02-5
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	2-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-one; 3',4'-Dimethoxy-2-bromoacetophenone; 2-Bromo-3',4'-dimethoxyacetophenone; 1-(3,4-Dimethoxyphenyl)-2-bromoethanone; α-Bromo-3,4-dimethoxyacetophenone; NSC 406916; 2-Bromoveratryl ketone
EINECS	217-403-4

Quality Control

Our 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.