Description

1-[2-(Trifluoromethyl)-4-Quinolyl]Hydrazine is a specialized heterocyclic building block featuring a hydrazine moiety attached to a trifluoromethyl-substituted quinoline core. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in developing novel pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Chemical Research & Development: Serves as a versatile building block for creating libraries of novel heterocyclic compounds for screening.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for catalysis.
• Academic Research: Utilized in universities and institutes for studying fluorinated heterocycle chemistry and reaction mechanisms.

Basic Information

Product Name	1-[2-(Trifluoromethyl)-4-Quinolyl]Hydrazine
CAS No.	1828-97-3
Molecular Formula	C10H8F3N3
Molecular Weight	227.19 g/mol
Synonyms	1-(2-(Trifluoromethyl)quinolin-4-yl)hydrazine; 4-Hydrazino-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-quinolylhydrazine; 1-Hydrazino-2-trifluoromethyl-4-quinoline; 1-(2-Trifluoromethyl-4-quinolyl)hydrazine; 1828-97-3; 4-Quinolinehydrazine, 2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethyl)-4-Quinolyl]Hydrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.