Description

2-Hydroxy-6-Methyl-4-(Trifluoromethyl)Quinoline is a high-purity, fluorinated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-cancer agents.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and insecticides where the trifluoromethyl group imparts improved lipophilicity and biological efficacy.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or pharmacophore in probe design.
• Catalyst Ligand Development: The quinoline scaffold can be modified to create novel ligands for transition metal catalysis in asymmetric synthesis.

Basic Information

Product Name	2-Hydroxy-6-Methyl-4-(Trifluoromethyl)Quinoline
CAS No.	1828-96-2
Molecular Formula	C₁₁H₈F₃NO
Molecular Weight	227.18 g/mol
Synonyms	4-(Trifluoromethyl)-6-methyl-2-quinolinol; 6-Methyl-4-(trifluoromethyl)quinolin-2-ol; 2-Quinolinol, 6-methyl-4-(trifluoromethyl)-; 2-Hydroxy-6-methyl-4-trifluoromethylquinoline; 4-Trifluoromethyl-6-methyl-2-hydroxyquinoline; 6-Methyl-2-hydroxy-4-trifluoromethylquinoline; 2-Hydroxy-6-methyl-4-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methyl-4-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.