Description

4-Iodophenylacetic Acid is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive iodophenyl moiety that can be further functionalized via cross-coupling reactions, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications ranging from active pharmaceutical ingredient (API) development to the creation of specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules via Suzuki, Heck, or Sonogashira cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require halogenated aromatic components.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating advanced organic electronic materials and liquid crystal displays (LCDs) due to its rigid, halogenated structure.
• Peptide Mimetics & Bioconjugation: The carboxylic acid group allows for amide bond formation, enabling its use in creating peptide analogs or for bioconjugation linker chemistry.
• Metal-Organic Framework (MOF) Synthesis: Acts as an organic linker or a functionalized precursor in the construction of porous coordination polymers and MOFs for catalysis or gas storage.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling chemistry and as a standard in analytical method development.

Basic Information

Product Name	4-Iodophenylacetic Acid
CAS No.	1798-06-7
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	(4-Iodophenyl)acetic Acid; p-Iodophenylacetic Acid; 2-(4-Iodophenyl)acetic Acid; 4-Iodobenzeneacetic Acid; NSC 404058; USAF EK-1777; α-(p-Iodophenyl)acetic Acid; (p-Iodophenyl)ethanoic Acid
EINECS	217-283-6

Quality Control

Our 4-Iodophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.