Description

Piperidine, 1-(Bromoacetyl)- (7Ci,8Ci,9Ci) CAS NO 1796-25-4 is a versatile bromoacetyl derivative of piperidine, serving as a critical bifunctional building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromoacetyl group and a piperidine ring, makes it an essential intermediate for constructing complex nitrogen-containing frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and fungicides that incorporate the piperidine moiety for enhanced biological activity.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and in organic methodology development as an alkylating agent.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Chemistry: Employed to introduce constrained piperidine scaffolds into peptide analogs to improve metabolic stability and bioavailability.
• Polymer Modification: Functional monomer for creating specialty polymers with tailored properties for advanced material science applications.

Basic Information

Item	Detail
Product Name	Piperidine, 1-(Bromoacetyl)- (7Ci,8Ci,9Ci)
CAS No.	1796-25-4
Molecular Formula	C7H12BrNO
Molecular Weight	206.08 g/mol
Synonyms	1-(Bromoacetyl)piperidine; N-(Bromoacetyl)piperidine; α-Bromo-1-piperidineacetamide; 2-Bromo-1-(piperidin-1-yl)ethanone; Bromoacetylpiperidine; N-Bromoacetylpiperidine; 1-Piperidineacetamide, α-bromo-; Ethanone, 2-bromo-1-(1-piperidinyl)-
EINECS	217-279-8

Quality Control

Every batch of Piperidine, 1-(Bromoacetyl)- is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard quality assurance protocol aligns with cGMP principles where applicable, and we support custom purity requirements for research and commercial-scale projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.