Description

Spiro[5.5]Undecan-2-One CAS NO 1781-81-3 is a high-purity, bicyclic ketone compound valued for its unique spirocyclic structure, which serves as a versatile and sophisticated building block in advanced organic synthesis. This compound matters because it provides a rigid, three-dimensional framework essential for constructing complex molecular architectures in pharmaceutical and material science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging its structural complexity for enhanced biological activity.
• Advanced Material Science: Serves as a precursor for ligands, catalysts, and monomers used in creating polymers with specific thermal or mechanical properties.
• Fragrance & Flavor Chemistry: Employed in the synthesis of high-value, musky or amber-type fragrance ingredients due to its stable macrocyclic-like character.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, including studies on ring formation and stereoselective reactions.

Basic Information

Product Name	Spiro[5.5]Undecan-2-One
CAS No.	1781-81-3
Molecular Formula	C₁₁H₁₈O
Molecular Weight	166.26 g/mol
Synonyms	Spiro[5.5]undecan-2-one; 2-Oxaspiro[5.5]undecane; 2-Oxaspiro(5.5)undecane; Spiro-5.5-undecan-2-one; 1781-81-3; NSC 102016; 1-Oxaspiro[5.5]undecan-2-one (tautomer)
EINECS	217-227-4

Quality Control

Our Spiro[5.5]Undecan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.