Description

4'-Methylthioacetophenone is a specialized organic compound featuring a methylthio group attached to the para position of an acetophenone core. This structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or sulfone functionalities.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced functional materials.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing certain sulfur-containing aroma compounds.
• Organic Synthesis Research: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Item	Details
Product Name	4'-Methylthioacetophenone
CAS No.	1778-09-2
Molecular Formula	C9H10OS
Molecular Weight	166.24 g/mol
Synonyms	1-[4-(Methylthio)phenyl]ethanone; 4-(Methylthio)acetophenone; p-Methylthioacetophenone; 4-Acetylphenyl methyl sulfide; Methyl 4-acetylphenyl sulfide; 4-Methylmercaptoacetophenone; 4-Acetylthioanisole
EINECS	217-208-6

Quality Control

Our 4'-Methylthioacetophenone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.