Description

trans-4-Chloro-2-Buten-1-Ol is a versatile chlorinated allylic alcohol building block with significant synthetic utility. This compound is valued for its bifunctional reactivity, featuring both a reactive chloro group and a hydroxyl group, making it a key intermediate in the synthesis of more complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocycles, active pharmaceutical ingredients (APIs), and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly in the development of antiviral or anti-inflammatory agents.
• Agrochemical Synthesis: Used as a building block in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Research: Employed in academic and industrial R&D for studying nucleophilic substitution reactions, cyclization processes, and as a scaffold for library synthesis.

Basic Information

Product Name	trans-4-Chloro-2-Buten-1-Ol
CAS No.	1775-39-9
Molecular Formula	C4H7ClO
Molecular Weight	106.55 g/mol
Synonyms	(E)-4-Chloro-2-buten-1-ol; (E)-4-Chlorobut-2-en-1-ol; trans-4-Chlorobut-2-en-1-ol; 4-Chloro-2-buten-1-ol, (E)-; 2-Buten-1-ol, 4-chloro-, (E)-; 4-Chloro-crotyl alcohol; (E)-4-Chlorocrotyl alcohol; 4-Chloro-2-butenol
EINECS	217-207-3

Quality Control

Our trans-4-Chloro-2-Buten-1-Ol is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.