Description

4'-Bromo-4-Methanesulfonyl-Biphenyl is a high-purity, versatile biphenyl derivative characterized by its bromo and methanesulfonyl functional groups. This compound serves as a critical synthetic intermediate in advanced organic chemistry, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry and material science development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other therapeutic areas.
• Material Science Research: Used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, due to its rigid biphenyl core.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides and fungicides, leveraging its halogen and sulfone moieties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for catalysis and molecular recognition studies.

Basic Information

Product Name	4'-Bromo-4-Methanesulfonyl-Biphenyl
CAS No.	1774-28-3
Molecular Formula	C13H11BrO2S
Molecular Weight	311.20 g/mol
Synonyms	4-Bromo-4'-methylsulfonylbiphenyl; [1,1'-Biphenyl]-4-sulfonic acid, 4'-bromo-, methyl ester; 4-(4-Bromophenyl)phenyl methyl sulfone; 4'-Bromo-4-(methylsulfonyl)biphenyl; 4-Bromo-4'-(methylsulfonyl)-1,1'-biphenyl; 4'-Bromobiphenyl-4-yl methyl sulfone; Methyl 4'-bromo[1,1'-biphenyl]-4-yl sulfone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-4-Methanesulfonyl-Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.