Description

(4-Dimethylamino-Phenyl)-Phosphonic Acid Diethyl Ester is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique structure, featuring both a phosphonic ester group and a dimethylamino-substituted aromatic ring, makes it a valuable building block for creating complex molecules with tailored properties. This high-purity chemical is essential for research and development laboratories and industrial manufacturers in the pharmaceutical and agrochemical sectors seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing specific biological activity profiles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and plant growth regulators, leveraging its phosphonate moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated phosphine-based ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of functional polymers, flame retardants, or metal-chelating agents due to its reactive phosphonic ester group.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and other transformations to introduce the (dimethylaminophenyl)phosphonate functional group into target molecules.

Basic Information

Product Name	(4-Dimethylamino-Phenyl)-Phosphonic Acid Diethyl Ester
CAS No.	1754-43-4
Molecular Formula	C12H20NO3P
Molecular Weight	257.26 g/mol
Synonyms	Diethyl (4-Dimethylaminophenyl)phosphonate; Diethyl P-(Dimethylamino)phenylphosphonate; (4-Dimethylaminophenyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[4-(Dimethylamino)phenyl]-, Diethyl Ester; Diethyl 4-(Dimethylamino)phenylphosphonate; (p-Dimethylaminophenyl)phosphonic Acid Diethyl Ester; 4-(Dimethylamino)benzenephosphonic Acid Diethyl Ester
EINECS	217-150-5

Quality Control

Our production of (4-Dimethylamino-Phenyl)-Phosphonic Acid Diethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full transparency and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.