Description

Diethyl(4-Nitrophenyl)Phosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical synthetic intermediate. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the synthesis of biologically active compounds and advanced materials. This product is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators that require the 4-nitrophenyl phosphonate moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in metal-catalyzed coupling reactions and organocatalysis.
• Material Science Research: Employed in the development of novel polymers, flame retardants, and surface-modifying agents.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and inhibitors for studying enzymatic processes.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	Diethyl(4-Nitrophenyl)Phosphonate
CAS No.	1754-42-3
Molecular Formula	C10H14NO5P
Molecular Weight	259.20 g/mol
Synonyms	Diethyl p-Nitrophenylphosphonate; Phosphonic acid, P-(4-nitrophenyl)-, diethyl ester; (4-Nitrophenyl)phosphonic acid diethyl ester; Diethyl 4-nitrophenylphosphonate; Diethyl (4-nitrophenyl)phosphate; EINECS 217-147-7
EINECS	217-147-7

Quality Control

Our Diethyl(4-Nitrophenyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of our global B2B clients. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.