Description

[(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxo-Hexoxy]Phosphonic Acid is a high-purity, structurally defined phosphonic acid derivative of N-acetylneuraminic acid, offering a critical building block for advanced biochemical synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds to develop novel glycoconjugates, enzyme inhibitors, and pharmaceutical intermediates. It is particularly valuable for the pharmaceutical, biotechnology, and advanced chemical synthesis sectors where stereochemical purity and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of sialic acid analogs and neuraminidase inhibitors for antiviral drug development.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to sialidases, glycosyltransferases, and carbohydrate metabolism.
• Glycoconjugate Synthesis: Acts as a specialized building block for creating complex oligosaccharides, glycopeptides, and glycolipids with defined biological activity.
• Probe and Diagnostic Development: Utilized in the design of molecular probes for labeling, imaging, and detecting specific carbohydrate-binding proteins or pathogens.
• Chemical Biology Tool: Employed to study cell surface interactions, signaling pathways, and the role of sialic acids in infection and immunity.

Basic Information

Product Name	[(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxo-Hexoxy]Phosphonic Acid
CAS No.	1746-32-3
Molecular Formula	C8H16NO10P
Molecular Weight	293.19 g/mol
Synonyms	5-Acetamido-2,3,4-trihydroxy-6-oxohexylphosphonic Acid; N-Acetylneuraminic Acid Phosphonate Derivative; Sialic Acid Phosphonic Acid Analog; (2R,3S,4R,5R)-5-(Acetylamino)-2,3,4-trihydroxy-6-oxohexylphosphonic Acid; Neu5Ac Phosphonate; 1746-32-3; Phosphono-N-acetylneuraminic acid derivative
EINECS	Contact for details

Quality Control

Our production of [(2R,3S,4R,5R)-5-Acetamido-2,3,4-Trihydroxy-6-Oxo-Hexoxy]Phosphonic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.