Description

Alpha,α-Trehalose 6,6'-Diphosphate is a high-purity, phosphorylated derivative of the natural disaccharide trehalose. This compound serves as a critical biochemical precursor and research standard, offering unique value in metabolic pathway studies and specialized bioprocesses. It is primarily sought by research institutions, diagnostic manufacturers, and biotechnology companies engaged in advanced enzymology, carbohydrate chemistry, and the development of novel biosensors or therapeutic agents.

Application

• Biochemical Research: Essential substrate for studying trehalose metabolism, enzyme kinetics (e.g., trehalose phosphatases), and signal transduction pathways in microorganisms and plants.
• Diagnostic Reagent Manufacturing: Used as a key component in enzymatic assay kits for quantifying metabolic activity or detecting specific biological markers.
• Enzyme Substrate & Standard: Serves as a high-purity reference standard and specific substrate for quality control and activity assays of phosphorylating/dephosphorylating enzymes.
• Metabolomics & Cell Signaling Studies: A crucial intermediate for investigating stress response mechanisms, anhydrobiosis, and energy storage processes in research models.
• Pharmaceutical Intermediates: Potential starting material or intermediate in the synthesis of novel therapeutic compounds targeting metabolic disorders.
• Specialty Bioprocessing: May be utilized in fermentation media or as a component in specialized biocatalytic processes requiring phosphorylated sugars.

Basic Information

Product Name	Alpha,α-Trehalose 6,6'-Diphosphate
CAS No.	1745-65-9
Molecular Formula	C₁₂H₂₀O₁₇P₂
Molecular Weight	546.22 g/mol
Synonyms	Trehalose 6,6'-Bisphosphate; α,α-Trehalose 6,6'-Diphosphate; O-α-D-Glucopyranosyl-(1→1)-α-D-glucopyranose 6,6'-Bis(dihydrogen phosphate); Trehalose-6,6'-diphosphoric acid; 6,6'-Bis-O-(dihydrogen phosphono)-α,α-trehalose; α-D-Glucopyranoside, α-D-glucopyranosyl, 6,6'-(dihydrogen phosphate); NSC 401464; Trehalose 6,6'-DP
EINECS	217-132-7

Quality Control

Our Alpha,α-Trehalose 6,6'-Diphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and in-vitro diagnostic grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.