Description

6-Trifluoromethyloxindole is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for the synthesis of active ingredients, particularly in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other biologically active small molecules.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology: Employed as a molecular scaffold or probe in drug discovery and biochemical research.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions and developing new synthetic methodologies.

Basic Information

Product Name	6-Trifluoromethyloxindole
CAS No.	1735-89-3
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	6-(Trifluoromethyl)-1,3-dihydro-2H-indol-2-one; 6-(Trifluoromethyl)oxindole; 2-Oxo-6-(trifluoromethyl)indoline; 1,3-Dihydro-6-(trifluoromethyl)-2H-indol-2-one; 6-Trifluoromethyl-2-indolinone; 6-Trifluoromethyl-2-oxindole; 1735-89-3; 6-CF3-oxindole
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyloxindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry, to support your R&D and scale-up activities. A Certificate of Analysis (COA) is available for every batch, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.