Description

(S)-(+)-2-Methylbutyric Acid is a high-purity, single-enantiomer chiral carboxylic acid with a characteristic cheesy, fruity odor. This optically active compound is a critical chiral building block and flavor/fragrance intermediate, offering significant value in synthesizing enantiomerically pure products. It is essential for manufacturers in the pharmaceutical, flavor & fragrance, and agrochemical industries seeking to produce high-value, stereospecific compounds.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system drugs.
• Flavor & Fragrance Industry: Used as a flavoring agent and aroma chemical to impart cheesy, fruity, or nutty notes in food products, beverages, and perfumes.
• Agrochemical Synthesis: Serves as a precursor for chiral pesticides and herbicides, where the specific stereochemistry can influence biological activity.
• Liquid Crystal Materials: Employed in the production of chiral dopants for liquid crystal displays (LCDs).
• Asymmetric Catalysis: Utilized as a chiral auxiliary or ligand in asymmetric synthesis to control stereoselectivity.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway analysis.

Basic Information

Product Name	(S)-(+)-2-Methylbutyric Acid
CAS No.	1730-91-2
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(S)-(+)-2-Methylbutanoic Acid; (S)-2-Methylbutyric Acid; L-2-Methylbutyric Acid; (S)-2-Methylbutanoic Acid; Dextrorotatory 2-Methylbutyric Acid; (2S)-2-Methylbutanoic Acid; Active Valeric Acid; Ethylmethylacetic Acid (S-form)
EINECS	217-070-6

Quality Control

Our (S)-(+)-2-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC or GC, to ensure compliance with exacting standards for enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. As a strong acid/organic solvent, it should be stored separately from bases, oxidizing agents, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (e.e.) (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]D20	+15.0° to +20.0° (c=1, EtOH)
Refractive Index nD20	1.405 - 1.415
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.