Description

4-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a halogenated quinoline scaffold with a trifluoromethyl group, offering versatile reactivity and the ability to modulate the physicochemical properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications, leveraging the bioisosteric properties of the trifluoromethyl group.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the quinoline core contributes to biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport layers.
• Ligand and Catalyst Development: The nitrogen-containing heterocycle can be functionalized to create novel ligands for metal catalysis or organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: An important substrate for investigating the introduction and transformation of fluorine-containing groups in complex molecular architectures.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	4-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline
CAS No.	1701-25-3
Molecular Formula	C11H7ClF3N
Molecular Weight	245.63 g/mol
Synonyms	4-Chloro-8-methyl-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-chloro-8-methylquinoline; 8-Methyl-4-chloro-2-trifluoromethylquinoline; Quinoline, 4-chloro-8-methyl-2-(trifluoromethyl)-; 1701-25-3; 4-Chloro-8-methyl-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.