Description

4-Hydroxy-6-Methoxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and methoxy substituents. This compound is essential for advanced research and development, particularly in the synthesis of complex molecules where its specific substitution pattern imparts desirable electronic and steric properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing organic light-emitting diodes (OLEDs), liquid crystals, and other functional electronic materials.
• Chemical Biology Probe Development: Employed in the design of fluorescent tags and molecular probes for studying biological processes.
• Catalyst Ligand Synthesis: Utilized as a building block for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Academic & Industrial R&D: A fundamental research chemical for exploring new reactions and synthesizing libraries of novel quinoline derivatives.

Basic Information

Product Name	4-Hydroxy-6-Methoxy-2-(Trifluoromethyl)Quinoline
CAS No.	1701-21-9
Molecular Formula	C₁₁H₈F₃NO₂
Molecular Weight	243.18 g/mol
Synonyms	2-(Trifluoromethyl)-6-methoxy-4-quinolinol; 6-Methoxy-2-(trifluoromethyl)-4-quinolinol; 4-Quinolinol, 6-methoxy-2-(trifluoromethyl)-; 4-Hydroxy-6-methoxy-2-trifluoromethylquinoline; 6-Methoxy-2-trifluoromethylquinolin-4-ol; 2-Trifluoromethyl-6-methoxy-4-hydroxyquinoline; 4-Hydroxy-6-methoxy-2-(trifluoromethyl)quinoline; 1701-21-9
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-Methoxy-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.