Description

4-Hydroxy-2-(Trifluoromethyl)Quinoline is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a hydroxyl group and a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and material properties. This product is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental stability.
• Material Science Research: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and organic synthesis for structure-activity relationship (SAR) studies.
• Fluorine Chemistry: An important reagent for introducing the trifluoromethyl group into complex molecules, leveraging fluorine's unique properties.

Basic Information

Product Name	4-Hydroxy-2-(Trifluoromethyl)Quinoline
CAS No.	1701-18-4
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	2-(Trifluoromethyl)-4-quinolinol; 4-Hydroxy-2-trifluoromethylquinoline; 2-Trifluoromethyl-4-hydroxyquinoline; 4-Quinolinol, 2-(trifluoromethyl)-; 4-Hydroxy-2-(trifluoromethyl)quinoline; HQ-CF3; TFMQ
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.