Description

3,6-Di-2-Pyridyl-1,2,4,5-Tetrazine is a heterocyclic organic compound belonging to the s-tetrazine family, recognized for its distinctive deep red to purple color and its role as a versatile building block in advanced materials science. This compound is highly valued for its strong electron-accepting properties and its ability to participate in inverse electron-demand Diels-Alder (iEDDA) reactions, which are exceptionally fast and bioorthogonal. It is a critical reagent for researchers and manufacturers in pharmaceuticals, polymer chemistry, and materials engineering who require precise, high-performance linkers and functionalization agents. The compound's unique reactivity profile makes it indispensable for creating smart materials, bioconjugates, and functional polymers.

Application

• Bioorthogonal Chemistry & Bioconjugation: As a key component in iEDDA click chemistry for labeling biomolecules, developing antibody-drug conjugates (ADCs), and live-cell imaging probes.
• Polymer & Materials Science: Serving as a cross-linking agent or monomer for synthesizing functional polymers, conductive materials, and self-healing hydrogels.
• Pharmaceutical Research: Utilized in the synthesis of novel drug candidates and as a linker for prodrug activation strategies.
• Dyes & Pigments: Acting as a precursor for high-performance dyes and pigments due to its intense coloration and stability.
• Coordination Chemistry & Ligand Synthesis: Functioning as a chelating ligand for transition metals in catalyst design and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A fundamental research chemical for exploring new reactions in synthetic organic chemistry and materials development.

Basic Information

Item	Details
Product Name	3,6-Di-2-Pyridyl-1,2,4,5-Tetrazine
CAS No.	1671-87-0
Molecular Formula	C12H8N6
Molecular Weight	236.23 g/mol
Synonyms	3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine; 3,6-Bis(2-pyridyl)-1,2,4,5-tetrazine; 2,2'-(1,2,4,5-Tetrazine-3,6-diyl)dipyridine; DPTZ; Di-2-pyridyl tetrazine; 3,6-Di-2-pyridyl-s-tetrazine; 3,6-Di(2-pyridyl)-1,2,4,5-tetrazine
EINECS	Contact for details

Quality Control

Our 3,6-Di-2-Pyridyl-1,2,4,5-Tetrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to relevant ISO guidelines, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent potential degradation.

Specification

Item	Specification
Appearance	Dark red to purple crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.