Description

2-(2-Fluorophenyl)-4-Quinolinecarboxylic Acid is a specialized fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its unique fluorinated aromatic structure imparts desirable biological and physicochemical properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Fluorescent Probe Development: The quinoline core can be utilized in the design of fluorescent markers and sensors for biochemical assays.

Basic Information

Product Name	2-(2-Fluorophenyl)-4-Quinolinecarboxylic Acid
CAS No.	1647-89-8
Molecular Formula	C₁₆H₁₀FNO₂
Molecular Weight	267.26 g/mol
Synonyms	2-(2-Fluorophenyl)quinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 2-(2-fluorophenyl)-; 2-(o-Fluorophenyl)-4-quinolinecarboxylic acid; 2-(2-Fluorophenyl)-4-quinolincarboxylic acid; 2-(2-Fluorophenyl)cinchoninic acid; 2-(2-Fluorophenyl)-4-carboxyquinoline; 2-(2-Fluorophenyl)-4-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)-4-Quinolinecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.