Description

Ethyl Bis(Trimethylsilyl)-Phosphate is a specialized organosilicon reagent featuring a phosphate ester core protected by trimethylsilyl groups. This compound matters as a versatile intermediate and protecting group agent, offering enhanced stability and reactivity for advanced synthetic chemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as nucleotide synthesis and the preparation of modified phosphates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleotide analogs and prodrugs.
• Protecting Group Reagent: Used to protect phosphate groups during complex multi-step organic syntheses.
• Agrochemical Synthesis: Intermediate in the production of specialized pesticides and herbicides.
• Material Science: Precursor for flame retardants and specialty polymers.
• Chemical Research: Valuable reagent for developing new phosphorylation methodologies.
• Ligand Synthesis: Used in the preparation of phosphorus-containing ligands for catalysis.

Basic Information

Product Name	Ethyl Bis(Trimethylsilyl)-Phosphate
CAS No.	1641-57-2
Molecular Formula	C8H23O4PSi2
Molecular Weight	270.41 g/mol
Synonyms	Ethyl Bis(trimethylsilyl) Phosphate; Ethyl Di(trimethylsilyl) Phosphate; Di(trimethylsilyl) Ethyl Phosphate; Phosphoric Acid, Ethyl Ester, Bis(trimethylsilyl) Ester; Ethoxybis(trimethylsiloxy)phosphine; O,O-Bis(trimethylsilyl) Ethyl Phosphate; TMS-Ethyl Phosphate
EINECS	Contact for details

Quality Control

Our Ethyl Bis(Trimethylsilyl)-Phosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or 31P NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.