Description

6-Chloroquinazoline-2,4(1H,3H)-Dione is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its functionalized quinazoline-dione scaffold, which serves as a critical precursor for constructing more complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage the quinazoline core.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Material Science Precursor: Can be utilized in the development of specialty chemicals, dyes, and functional organic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	6-Chloroquinazoline-2,4(1H,3H)-Dione
CAS No.	1640-60-4
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	6-Chloro-1H,3H-quinazoline-2,4-dione; 6-Chloro-2,4-dihydroxyquinazoline; 6-Chloroquinazoline-2,4-diol; 2,4-Dihydroxy-6-chloroquinazoline; 6-Chloro-2,4(1H,3H)-quinazolinedione; 6-Chlorobarbituric acid analogue; Quinazoline-2,4(1H,3H)-dione, 6-chloro-
EINECS	Contact for details

Quality Control

Our 6-Chloroquinazoline-2,4(1H,3H)-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.