Description

Diethyl Phenylphosphonite is a versatile organophosphorus compound widely used as a key reagent in organic synthesis. Its primary value lies in its role as a phosphonylation agent, enabling the efficient construction of carbon-phosphorus bonds. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries. The compound is particularly valued for its application in the synthesis of biologically active molecules and specialized ligands.

Application

• Key intermediate in the synthesis of pharmaceutical actives, including antiviral and anticancer agents.
• Precursor for the production of organophosphorus ligands used in homogeneous catalysis and cross-coupling reactions.
• Building block for agrochemicals, such as herbicides and plant growth regulators.
• Reagent in the preparation of flame retardants and other specialty additives for polymers.
• Used in material science for the synthesis of phosphonate-based metal-organic frameworks (MOFs) and surface modifiers.
• Essential for academic and industrial research and development in novel synthetic methodologies.

Basic Information

Product Name	Diethyl Phenylphosphonite
CAS No.	1638-86-4
Molecular Formula	C10H15O2P
Molecular Weight	198.20 g/mol
Synonyms	Phenylphosphonic Acid Diethyl Ester; Diethoxy(phenyl)phosphine; Diethyl Phenylphosphonate (common misnomer, refers to oxidized form); Ethyl Phenylphosphonite; Phenyldiethoxyphosphine; P,P-Diethoxy-phenylphosphine; NSC 66495; Phosphonic acid, P-phenyl-, diethyl ester
EINECS	216-685-7

Quality Control

Our Diethyl Phenylphosphonite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Due to its sensitivity to moisture and oxygen, containers should be purged with inert gas after each use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.