Description

Diethyl (Formylmethyl)Phosphonate is a versatile organophosphorus compound, specifically a phosphonate ester bearing a formyl group. This chemical is a crucial building block in organic synthesis, valued for its role as a reagent in the Horner-Wadsworth-Emmons (HWE) olefination reaction to synthesize α,β-unsaturated carbonyl compounds. It is essential for R&D chemists and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing α,β-unsaturated ester or ketone moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific olefin linkages.
• Fine Chemical Manufacturing: Serves as a critical building block for fragrances, flavors, and specialty polymers where precise carbon-carbon double bond formation is needed.
• Material Science Research: Employed in the development of novel organic materials and ligands for catalysis.
• Academic & Industrial R&D: A staple reagent in organic synthesis laboratories for method development and complex molecule construction.

Basic Information

Product Name	Diethyl (Formylmethyl)Phosphonate
CAS No.	1606-75-3
Molecular Formula	C6H13O4P
Molecular Weight	180.14 g/mol
Synonyms	(Formylmethyl)phosphonic Acid Diethyl Ester; Diethyl (Oxomethyl)methylphosphonate; Diethyl Formylmethylphosphonate; (Formylmethyl)phosphonic Acid Diethyl Ester; Diethyl P-Formylmethylphosphonate; Ethyl (Diethoxyphosphinyl)acetate (tautomer); Diethyl Phosphonoacetate Aldehyde; EINECS 216-525-0
EINECS	216-525-0

Quality Control

Our Diethyl (Formylmethyl)Phosphonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) after opening to maintain purity and prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.