Description

2-Fluoro-7,8,9,10-Tetrahydro-6H-Cyclohepta[B]Quinoline-11-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring quinoline structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by pharmaceutical R&D organizations, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers engaged in developing next-generation drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Used in advanced organic transformations, including cross-coupling reactions and cyclizations, to construct polycyclic frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Agrochemical Research: Potential application as an intermediate in the development of new-generation herbicides or fungicides with novel modes of action.
• Material Science: Investigated as a precursor for organic electronic materials due to its fused aromatic system and potential for functionalization.

Basic Information

Product Name	2-Fluoro-7,8,9,10-Tetrahydro-6H-Cyclohepta[B]Quinoline-11-Carboxylic Acid
CAS No.	1555-11-9
Molecular Formula	C15H14FNO2
Molecular Weight	259.28 g/mol
Synonyms	2-Fluoro-6,7,8,9-tetrahydrocyclohepta[b]quinoline-11-carboxylic acid; 11-Carboxy-2-fluoro-6,7,8,9-tetrahydrocyclohepta[b]quinoline; 2-Fluoro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylic acid; 1555-11-9; 2-Fluoro-6,7,8,9-tetrahydro-5H-cyclohepta[b]quinoline-11-carboxylic acid; 2-Fluoro-5,6,7,8,9,10-hexahydrocyclohepta[b]quinoline-11-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-7,8,9,10-Tetrahydro-6H-Cyclohepta[B]Quinoline-11-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled in a compatible environment for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.